Blood flow and
metabolism are not
uniform throughout the
brain. Testing of new
drugs should always
include looking for
effects on blood flow
and metabolism in the
brain.
OBJECTIVE:
Part time consulting for neuroscience research and pharmaceutical development
EDUCATION:
- Cognitive Neuroscience, Harvard University Extension School, 2005
- Nursing Update Certificate, Boston College, 2004
- Teacher Certification, UMASS Boston, 1993
- Nursing, Laboure College, Boston MA, 1992
COMPUTER SKILLS:
- HTML programming for website development & Yahoo SiteBuilder
- Microsoft Word & PowerPoint
- MEDITECH Nursing, Patient Care Inquiry (PCI), Order Entry, & Lab modules
CURRENT EMPLOYMENT:
- Nurse (per diem), Bridgewater State Hospital, Bridgewater MA, 2002-present
PAST EMPLOYMENT:
- Tutor for children with special needs, Diamond Middle School, Lexington MA, 2005
- Mental Health Worker (per diem), Bridgewater State Hospital, Bridgewater MA, 1991-2002
- Programmer & Applications Consultant, MEDITECH, Westwood MA, 1994-1998
- Nurse, Westborough Admissions Unit, Middlesex Hospital, Waltham MA, 1993
- Nurse, Winthrop Hospital Psychiatric Unit, Winthrop MA, 1992
SPECIAL INTERESTS:
- Etiologies and brain impairments in developmental language delay, dyslexia, and autism
- Research, publication, and conference presentations (mostly on autism, many online)
CAREER BEFORE NURSING:
- Software Engineer & Instructor (8 years), Digital, Maynard MA, 1979-1990
- Educational background in computer science and biochemistry, PhD Boston University 1975
- Mother of four sons (now grown up)
The blood brain barrier should prevent
bilirubin from entering the brain.
Synthetic vitamin K and antibiotics like
sulfisoxazole given to newborn infants
were found to breach the blood-brain
barrier and cause kernicterus. All
drugs used in the neonatal period
should be tested for their potential to
disrupt the blood-brain barrier.
PUBLICATIONS:
Simon EN (2006) Comment on "Asperger syndrome: Familial, pre- and perinatal factors" by
Gillberg and Cederlund. J Autism Dev Disord. 2006 Feb;36(2):291-2. [letter]
Simon EN (2005) Auditory agnosia caused by a tectal germinoma. Neurology. 2005
Jul 26;65(2):339 [letter]; author reply 339.
- Also online at http://www.neurology.org/cgi/eletters/63/12/2387
Simon EN (2004) Autism as a birth defect. Birth Defects Res Part A Clin Mol Teratol.
2004 Jun;70(6):416.
Simon EN (2004) The lessons of MMR. Lancet. 2004 May 1;363(9419):1473-4.
Simon N (2000) Autism's home in the brain. Neurology 54:269-270.
Simon N. (1999) Auditory dysfunction in autism: a submicroscopic form of Wernicke's
encephalopathy? Journal of Autism and Developmental Disorders 29:426-427.
Simon N. (1999) The auditory system, brain maturation, and development in autistic children.
Journal of Autism and Developmental Disorders 29:94-95.
Simon N. (1998) Hemoglobin and the brain: a piece of the autism puzzle? Journal of Autism and
Developmental Disorders 28:579-580.
Simon N. (1997) Autism and the inferior colliculus. Journal of Autism and Developmental
Disorders 27:494-496.
Simon N (1990) Infantile autism and Wernicke's encephalopathy. Medical Hypotheses
32:169-172.
Simon N (1978) Kaspar Hauser's recovery and autopsy: A perspective on neurological and
sociological requirements for language development. Journal of Autism and Childhood
Schizophrenia 8:209-217.
- Reprinted in J. Money and G. Williams (eds.) Traumatic Abuse and Neglect of Children at
Home, Chapter 6, pp 56-62. Johns Hopkins Press: Baltimore, 1979.
- Also reprinted in S. Chess and A. Thomas (eds.) Annual Progress in Child Psychiatry and
Child Development 1979, Vol. 12, Chapter 11, pp. 215-224, Brunner/Mazel: New York, 1979.
Simon N & Volicer L (1978) Neonatal asphyxia in the rat: Greater vulnerability of males and
persistent effects on brain monoamine synthesis. Journal of Neurochemistry 26:893-900.
Simon N (1975) Echolalic speech in childhood autism: Consideration of possible underlying loci
of brain damage. Archives of General Psychiatry 32:1439-1446, 1975.
- Reprinted in S. Chess and A. Thomas (eds.) Annual Progress in Child Psychiatry and Child
Development 1976, Vol. 9, Chapter 25, pp. 471-490, Brunner/Mazel: New York, 1977.
Simon EN (1975) Long-term Effects of Neonatal Asphyxia in the Rat. Doctoral Dissertation,
Boston University, Boston MA, 1974, 193 pp. University Microfilms, Ann Arbor MI, Order No.
7505520.
Resume - working version
From: Kety SS (1962) Regional
neurochemistry and its application to brain
function. In French, JD, ed, Frontiers in Brain
Research. New York: Columbia University
Press, pp 97-120.
From: Lucey JF. (1964). Kernicterus in asphyxiated newborn rhesus
monkeys. Experimental Neurology 9, 43-58.
Boston University School of Medicine, 1971
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