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Research Proposal
Motivation
Speech understanding
Inferior colliculus lesions
Brainstem aphasia
Plan
fMRI of the inferior colliculi
Subjects
Testing strategies
Predicted results
Working hypotheses
Language areas on fMRI
Effects of asphyxia at birth
Maturation of the brain
Time-table of myelination
Learning to speak "by ear"
Metabolism in the brain
Protective mechanisms
Catastrophic factors
Brainstem damage

References:
Auditory problems in autism
Vasodilation in adverse conditions to maintain optimum blood flow
53.        Shih TM, Scremin OU (1992) Cerebral blood flow and metabolism in
soman-induced convulsions. Brain Research Bulletin 28:735-42
54.        Kelly PA, Ritchie IM, McBean DE, Sharkey J, Olverman HJ (1995) Enhanced
cerebrovascular responsiveness to hypercapnia following depletion of central serotonergic
terminals. Journal of Cerebral Blood Flow and Metabolism 15:706-713
The Bohr Effect
55.        Jensen FB. Red blood cell pH, the Bohr effect, and other oxygenation-linked
phenomena in blood O2 and CO2 transport. Acta Physiol Scand. 2004 Nov;182(3):215-27.
January 2006
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Working version
under construction