Figure 13 – Autoradiograph,
blood flow in the brain
Figure 14 – Hemorrhagic
damage from thiamine
(vitamin B1) deficiency


Speech understanding
Subjects & tests
Predicted results
Hypotheses & rationale

References
Auditory agnosia
Asphyxia at birth
Human infants
Functional MRI
Presbyacusis
Fetal alcohol syndrome
fMRI of language processing
Trophic transmitters
Longterm outcome
Myelin maturation
Learning to speak
Kanner autism
Metabolism in the brain
Vasodilation response
The Bohr effect
Circulatory arrest
Brainstem damage
Thiamine deficiency
Autism & prenatal alcohol
Autism & valproic acid
Autism & infections
Autism & PKU
Autism & genetic disorders
Autism & medical disorders
Autism & perinatal problems
Figure 14: Damage to the inferior
colliculi in a human patient maintained
on prolonged parenteral feeding
lacking vitamin B1.  Hemorrhage
occurs with vasodilation, a protective
mechanism.  Compare with ischemic
damage in figure 3.
(from Vortmeyer et al. 1992).
Figure 13: Experiments on cerebral
circulation in cats showed greatest perfusion
of a radioactive tracer after 60 seconds, thus
greatest blood flow, in nuclei of the brainstem
auditory pathway. These auditory nuclei are
therefore vulnerable during a brief period of
circulatory arrest or asphyxia, and also to
metabolic disturbances caused by all other
etiologic conditions associated with autism.
(from Kety, 1962, with permission from
Columbia University Press)
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