Cortical and brainstem patterns of damage - as found in monkeys
Palmer and Rossdale compared their findings with the two patterns of
damage described by Myers in 1972 seen in monkeys subjected to hypoxia
and or asphyxia shortly before or after birth.  Myers subjected monkeys to
partial hypoxia late in gestation, which resulted in damage of the cerebral
cortex similar to that seen in human cases of cerebral palsy.  On the other
hand, when he inflicted catastrophic total asphyxia at birth for several
minutes, damage was restricted to the brainstem.  Palmer and Rossdale
found brainstem damage in foals who suffered apnea at birth, including
lesions of the inferior colliculi as had been the case in monkeys subjected to
asphyxia.


In 1976 and 1976 Palmer and Rossdale reported neuropathological changes
found in 18 foals that had exhibited signs of the "convulsive foal syndrome."  
A spectrum of changes in the brain were observed, including ischemic
necrosis within the cerebral cortex in nine of the foals, with involvement of the
diencephalon and brainstem in three of these.  Hemorrhagic damage of the
cerebrum, and sometimes the brainstem and cerebellum, was observed in
the other nine foals.