| During an hypoxic episode hemoglobin provides immediate adjustment that protects tissues of highest metabolic rate, such as brainstem nuclei in control of autonomic functions. This is the Bohr effect as described in one textbook: “Primitive organisms rely on diffusion through their environmental media to provide the oxygen needed for their metabolism and to remove the carbon dioxide produced. The active metabolism of mammalian tissues remote from the atmosphere is possible because of a mechanism which provides constant delivery of oxygen and removal of carbon dioxide. The magnitude of this task may be appreciated from the fact that a man oxidizing 3000 Cal. Of mixed food per day uses about 600 liters of oxygen (27 moles) and produces about 480 liters of carbon dioxide (22 moles). Through the action of hemoglobin, oxygen is abstracted from the air, carried within a few seconds to the most distant parts of the body, and delivered to the tissues at a pressure only slightly less than that which it existed in the atmosphere. The CO2 produced daily by the tissues becomes H2CO3, an acid, in an amount equivalent to 2 liters of concentrated hydrochloric acid; yet all this acid normally pours from the tissues, through the blood, and out of the lungs with a change in the pH of blood of no more than few hundredths of a pH unit.” White A, Handler P, Smith EL (1968) Principles of Biochemistry, fourth edition. New York: McGraw-Hill. P 758 – Chapter 32. Chemistry of Respiration |
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| Baltic Cruise Jun 17 - Jul 5 2006 Arrival in Frankfurt Copenhagen >>> ----------------------------- Viking Museum With the group Departure Setting sail Gdansk, Poland Vilnius, Lithuania Riga, Latvia To Sweden Stockholm To Finland Helsinki Tallin, Estonia St. Petersburg |
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| See also: http://en.wikipedia.org /wiki/Bohr_effect And, for future reference: http://www.museion.ku .dk/ and http://www.nbi.dk/NBA/ walk.pdf |
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| <<< 000 >>> |
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| . . . Lectures on board |